Technology Development
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In 1993 we reorganized the Biology and Biotechnology Research Program to increase emphasis on technology development to accelerate the research we do. Our technologies focus on aspects of molecular biology such as vector development, molecular genetic applications such as chromosome painting and high-resolution fluorescence in situ hybridization, software development for database interaction, networking in a client-server mode, and bioinstrumentation. The bioinstrumentation focus has been on image analysis for cytogenetic automation, robotics for automating the replication of microtiter dishes and for high-density filter preparations, flow cytometry, microfabrication techniques to create miniaturized chambers for high throughput PCR, as well as increasing the throughput and sensitivity of electrophoresis for DNA sequencing and fragment separations. Many of these technologies have been transferred to other laboratories and to industry.
For more information contact: Raymond Mariella (mariella1@llnl.gov)